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Exophthalmos as a first manifestation of small cell lung cancer: a long-term follow-up
M Konoglou1, P Zarogoulidis, K Porpodis
11st Pulmonary Department, University of Thessalia, Larissa, Greece.
Abstract:
Small cell lung cancer is characterized by rapid growth and early metastasis. Despite its sensitivity to cytotoxic therapy, until now treatments have failed to control or cure this disease in most patients. Orbital metastases are a rare manifestation of systemic malignancies. Breast and lung cancers represent more than two thirds of the primary cancer sites. Metastases to the eye and orbit develop in approximately 0.7-12% of patients with lung cancer. Here, we report a rare case of exophthalmos as the first manifestation of a metastatic carcinoma due to small cell lung cancer, and a 6-months follow-up with complete exophthalmic response to chemotherapy.
Insights
This study reports a rare case where exophthalmos was the initial sign of small cell lung cancer metastasis. Chemotherapy led to a complete resolution of the eye condition, offering hope for managing this rare presentation.
Area of Science:
- Oncology
- Ophthalmology
Background:
- Small cell lung cancer (SCLC) is aggressive, marked by rapid growth and early metastasis.
- While sensitive to chemotherapy, SCLC remains difficult to cure.
- Orbital metastases are uncommon but can arise from systemic cancers, particularly lung and breast cancers.