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Seminal vesicles: development, secretory products, and fertility.
1Department of Zoology and Physiology, University of Wyoming, Laramie 82071.
Archives of Andrology
|January 1, 1990
Summary
Seminal vesicle proteins, though not essential for fertility, aid in ensuring it. Biochemistry suggests cyclic adenosine monophosphate (cAMP) dependent phosphorylation may mediate sperm-seminal vesicle protein interactions.
Area of Science:
- Reproductive biology
- Biochemistry
- Developmental biology
Background:
- The seminal vesicle develops from the mesonephric duct.
- Seminal vesicle fluid contains a limited number of proteins, some of which exhibit insolubility and aggregate formation.
- These proteins play a role in ensuring male fertility.
Purpose of the Study:
- To describe the development of the seminal vesicle.
- To detail the recent biochemistry of seminal vesicle proteins.
- To present a biochemical model for sperm-seminal vesicle interactions.
Main Methods:
- Histological description of seminal vesicle development.
- Biochemical analysis of seminal vesicle fluid proteins.
- Biochemical modeling of protein-sperm interactions.
Main Results:
- Seminal vesicle proteins are few, can be insoluble, and form aggregates.
- Seminal vesicle fluid contributes to fertility.
- A model indicates cAMP dependent phosphorylation is a key interaction mechanism between sperm and seminal vesicle proteins.
Conclusions:
- Seminal vesicle protein biochemistry is characterized by aggregation and potential insolubility.
- Seminal vesicle fluid is important for optimizing fertility.
- Cyclic adenosine monophosphate (cAMP) dependent phosphorylation is proposed as a significant molecular interaction in reproduction.