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Updated: May 26, 2026

Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
Published on: February 8, 2022
Sex differences in perihemorrhagic edema evolution after spontaneous intracerebral hemorrhage
I Wagner1, B Volbers, S Kloska
1Department of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany. ingrid.wagner@uk-erlangen.de
Background And Purpose:
Clinical data on sex differences in perihemorrhagic edema (PHE) after intracerebral hemorrhage (ICH) are lacking.
Methods:
Patients with spontaneous supratentorial ICH who had received standard conservative treatment were identified retrospectively. PHE development was assessed over a 14-day period on follow-up CT scans (days 1, 2-4, 5-7, 8-11, and 12-14). ICH and PHE volumes were assessed semiautomatically and compared between men and women.
Results:
A total of 387 patients (233 men) were included. Starting at days 2-4, women showed lower PHE values (P < 0.05; days 2-4, 8-11) or a trend toward significance (P ≤ 0.1; days 5-7, 12-14).
Conclusions:
Female sex may predict lower PHE volumes.
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