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A Fluorescent Intravital Imaging Approach to Study Load-Induced Calcium Signaling Dynamics in Mouse Osteocytes
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Possible role of calcium permselectivity in bone adaptation

Thibault Lemaire1, Salah Naili

  • 1Université Paris Est, Laboratoire Modélisation et Simulation Multi Échelle, MSME UMR CNRS 8208, 61 Avenue du Général de Gaulle, 94010 Créteil, France. thibault.lemaire@univ-paris-est.fr

Medical Hypotheses
|January 7, 2012
PubMed
Summary

A new hypothesis suggests mechanical loading influences bone adaptation by altering calcium transport. Piezoelectric effects create electrical differences, impacting calcium levels and bone remodeling.

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