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Updated: May 26, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
Published on: December 9, 2021
Evaluation of aortic bioprosthesis stenosis by multidetector CT
Sophie Piérard1, Stéphanie Seldrum, Thierry Muller
1Division of Cardiology, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10-2881, B-1200 Brussels, Belgium.
Multidetector computed tomography effectively visualizes acute aortic bioprosthesis thrombosis, overcoming echocardiography limitations. Follow-up CT confirmed thrombus resolution and improved valve function after anticoagulation therapy.
Area of Science:
- Cardiovascular Imaging
- Medical Diagnostics
- Bioprosthetic Devices
Background:
- Echocardiography visualization of bioprosthetic valve leaflets is often limited by shadowing artifacts from metallic components.
- Determining the cause of bioprosthetic valve dysfunction can be challenging with traditional imaging modalities.
Observation:
- Two cases of acute aortic bioprosthesis thrombosis were successfully visualized using 256 slice-multidetector row computed tomography (CT).
- In one case, CT imaging compared to a prior exam 4 months earlier confirmed valve thrombosis.
- In the second case, follow-up CT after 2 months of oral anticoagulation demonstrated thrombus resolution and normalized valve opening.
Findings:
- Multidetector CT provides clear visualization of bioprosthesis thrombosis, a condition difficult to assess with echocardiography.
- CT imaging can track changes in thrombus burden and assess the effectiveness of anticoagulation therapy.
Implications:
- Multidetector CT is a valuable tool for diagnosing and monitoring acute aortic bioprosthesis thrombosis.
- This imaging technique can guide treatment decisions and assess therapeutic outcomes in patients with bioprosthetic heart valves.
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