Related Experiment Video
Updated: Aug 15, 2026

Image-based Flow Cytometry Technique to Evaluate Changes in Granulocyte Function In Vitro
Published on: December 26, 2014
[Principles of the morphofunctional classification of granulocyte deficiencies]
Abstract:
On the basis of qualitative and quantitative indexes of the plasmatic-cellular system of neutrophilic leukocyte /NL/ a classification of granulocytic deficiencies /GD/ is developed, 4 forms of GD are distinguished: agranulocytosis, granulocytasthenia, myeloproliferative conditions and inflammatory leukocytosis. As a clinicomorphological criterium of GD a triad is suggested that includes a tissue necrosis, microbism and inflammatory infiltration. Functional failure typical for every form of GD has it sown features.
Related Concept Videos
Multipotency of Hematopoietic Stem Cells
Lineage Commitment
Differentiation of Common Myeloid Progenitor Cells
Structure and Function of Leukocytes
White blood cells protect the body...
Classification of Leukocytes
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...

