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Related Concept Videos

Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...

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Related Experiment Videos

Management of neurogenic bowel dysfunction.

G Paris1, G Gourcerol, A M Leroi

  • 1ADEN EA4311/IFRMP 23, Physiology Unit, Rouen University Hospital, Rouen, France.

European Journal of Physical and Rehabilitation Medicine
|January 7, 2012
PubMed
Summary
This summary is machine-generated.

This review explores treatments for neurogenic bowel dysfunction (NBD). Pharmacological interventions show strong evidence for chronic constipation, but evidence for other conservative and surgical NBD treatments is limited.

Related Experiment Videos

Area of Science:

  • Neuroscience
  • Gastroenterology
  • Rehabilitation Medicine

Background:

  • Neurogenic bowel dysfunction (NBD) significantly impacts patients with neurologic diseases.
  • Management of NBD involves a range of conservative and surgical options.
  • Evidence supporting the efficacy of many NBD treatments is limited.

Purpose of the Study:

  • To review and synthesize evidence for various NBD treatments.
  • To propose stepwise management algorithms for NBD.
  • To identify effective interventions for constipation and fecal incontinence in NBD.

Main Methods:

  • Systematic literature review of English language articles.
  • Inclusion of randomized controlled studies, cohort studies, and case-control studies.
  • Identification of 79 relevant articles from an initial search of 577.

Main Results:

  • Limited evidence supports non-pharmacological conservative NBD treatments.
  • Strong evidence exists for pharmacological interventions, such as prokinetic agents, in chronic constipation.
  • Surgical interventions for NBD have limited supporting evidence.

Conclusions:

  • Bowel management in NBD requires a comprehensive, multi-faceted approach.
  • Pharmacological interventions are the most evidence-based treatment for chronic constipation in NBD.
  • Further research is needed to establish the effectiveness of many conservative and surgical NBD therapies.