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Thiamine in nutrition therapy.
Krishnan Sriram1, William Manzanares, Kimberly Joseph
1Department of Surgery, Room 3350, Stroger Hospital, 1901 West Harrison St, Chicago, IL 60612, USA. ksriram@cookcountyhhs.org
Summary
Thiamine (vitamin B1) deficiency, historically known as beriberi, can manifest in various ways, including neurological and cardiac issues. This review highlights its importance in nutrition therapy and provides guidance for prevention and management.
Area of Science:
- Nutrition Science
- Biochemistry
- Clinical Medicine
Background:
- Micronutrients, including vitamins and trace elements, are crucial for biological processes and enzymatic reactions.
- Historically, nutrition therapy has focused on macronutrients, often overlooking the significance of micronutrients.
- Deficiencies in micronutrients can lead to severe health consequences.
Purpose of the Study:
- To emphasize the critical role of vitamin B1 (thiamine) in nutrition therapy.
- To discuss that alcoholism is not the sole cause of thiamine deficiency.
- To provide practical strategies for preventing and managing thiamine deficiency states.
Main Methods:
- This is a review article, synthesizing existing knowledge on thiamine.
- It focuses on the clinical manifestations and nutritional importance of thiamine.
- The review offers practical guidance for clinicians.
Main Results:
- Thiamine deficiency, or beriberi, presents with diverse symptoms, including neurological abnormalities, mental changes, and congestive heart failure.
- Deficiency can occur in well-nourished individuals and may not always be suspected.
- Thiamine plays a vital role in fundamental biological processes and enzymatic functions.
Conclusions:
- Thiamine is essential for optimal nutrition therapy and overall health.
- Clinicians should consider thiamine deficiency even in patients who appear well-nourished.
- Early recognition and management of thiamine deficiency are crucial to prevent adverse outcomes.
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