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Updated: May 26, 2026

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Published on: July 2, 2018
[The heart rate variability in the acute lacunar cerebral infarct]
Insights
Acute lacunar stroke disrupts heart rate variability, indicating autonomic nervous system imbalance. This study reveals changes in heart rate control following lacunar infarcts.
Area of Science:
- Cardiology
- Neurology
- Autonomic Nervous System Research
Context:
- Lacunar infarcts are a common type of ischemic stroke.
- Autonomic nervous system (ANS) dysfunction can complicate stroke recovery.
- Heart rate variability (HRV) analysis offers insights into ANS activity.
Purpose:
- To investigate heart rate variability (HRV) disturbances in patients with acute lacunar cerebral infarct.
- To assess the impact of lacunar stroke on the autonomic control of heart rate.
Summary:
- This study examined 30 patients with acute lacunar cerebral infarct, excluding those with arrhythmias.
- Electrocardiogram (EKG) recordings and time/frequency domain HRV analysis were performed.
- Results showed significant HRV disturbances, including centralization of autonomic control, relative sympathetic dominance, and reduced parasympathetic activity, particularly in right carotid stroke cases.
Impact:
- Findings suggest that lacunar stroke significantly alters cardiac autonomic regulation.
- Understanding these HRV changes may aid in stroke prognostication and management.
- Highlights the link between cerebrovascular events and cardiovascular autonomic dysfunction.
Abstract:
Clinical-electrophysiological investigation has been performed in 30 patients with acute lacunar cerebral infarct. Patients with atrial fibrillation, severe extrasystole weren't included to the study. The control group includes 7 health volunteers. EKG registration within 5 minutes with time domain, frequency domain analysis have been made. Brain attack on the type of lacunar IS associates with evident HRV disturbances. Centralization of the heart rate autonomic control, caused by suprasegmental part of the vegetative nervous system hyperactivity occurs against a background relative sympaticothonia and decrease of parasympathetic nervous system. In case of right carotid stroke there is significant lowering of standard deviation of the RR intervals (p=0,024), triangular index (p<0,001), total power (p=0,016), increase of mode of the histogram distribution of RR intervals (p=0,002) and the proportion derived by the number of RR intervals, that match the value of mode (p=0,001).
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