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Related Experiment Video

Updated: May 26, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Upper gastrointestinal bleeding: a Jamaican perspective.

M Kaliamurthy1, M G Lee, M Mills

  • 1Department of Medicine, The University of the West Indies, Kingston 7, Jamaica, West Indies.

The West Indian Medical Journal
|January 10, 2012
PubMed
Summary
This summary is machine-generated.

Upper gastrointestinal bleeding (UGIB) is a common emergency, particularly in middle-aged men. Early endoscopy and proton pump inhibitors (PPIs) are key management strategies, with a 5.7% mortality rate observed in this Jamaican study.

Related Experiment Videos

Last Updated: May 26, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Clinical Research

Background:

  • Upper gastrointestinal bleeding (UGIB) is a frequent and serious medical emergency.
  • It is associated with significant patient morbidity, mortality, and healthcare costs.

Purpose of the Study:

  • To review the clinical characteristics, management approaches, and patient outcomes for UGIB.
  • Focus on patients treated at the University Hospital of the West Indies (UHWI), Jamaica.

Main Methods:

  • Retrospective review of 104 patients diagnosed with UGIB between January 2006 and December 2008.
  • Data collected included demographics, symptoms, risk factors, endoscopic findings, treatments, and outcomes.

Main Results:

  • The study population (mean age 55) comprised predominantly men (73 vs 31).
  • Leading causes included duodenal ulcer (28%), erosive gastritis (20%), and gastric ulcer (13%).
  • Intravenous proton pump inhibitors (PPIs) were administered to 91% of patients, with 80% undergoing upper GI endoscopy (EGD).

Conclusions:

  • UGIB predominantly affects middle-aged men, with non-steroidal anti-inflammatory drug (NSAID) use being a notable risk factor.
  • The observed mortality rate of 5.7% is comparable to other studies.
  • Early EGD and endoscopic therapy may reduce mortality in high-risk UGIB patients.