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Updated: May 26, 2026

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A Modified Co-Culture System for Understanding Granulosa-Theca Cell Interactions in the Bovine Ovary
Published on: September 19, 2025
[Granulosa cell tumor and pregnancy]
Ana Paula Machado1, Marina Moucho, Joanne Lopes
1Serviços de Obstetrícia e de Anatomia Patológica, Hospital de S. João, Porto.
Acta Medica Portuguesa
|January 10, 2012
Summary
A rare case of a large ovarian tumor complicated a pregnancy, diagnosed via ultrasound. Symptoms at 35 weeks suggested torsion, highlighting risks in pregnant patients.
Area of Science:
- Gynecology
- Obstetrics
- Oncology
Background:
- Ovarian tumors during pregnancy are uncommon but can pose significant risks.
- Juvenile granulosa cell tumors (JGCTs) are rare ovarian neoplasms, typically affecting young women.
Observation:
- A large JGCT was incidentally discovered during a routine ultrasound at 33 weeks of gestation.
- The patient presented with pain, nausea, and vomiting at 35 weeks gestation, raising suspicion for ovarian torsion.
Findings:
- The case highlights the diagnostic challenge of large ovarian masses in late pregnancy.
- Ovarian torsion is a critical complication that can occur with ovarian tumors during gestation.
Implications:
- Early detection and management of ovarian tumors in pregnancy are crucial for maternal and fetal well-being.
- This case underscores the importance of considering adnexal masses and their complications in pregnant patients presenting with acute abdominal symptoms.
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