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Updated: May 26, 2026

Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation
Published on: June 21, 2021
Mechanisms and dynamics in the thiol/disulfide redox regulatory network: transmitters, sensors and targets
Janine König1, Meenakumari Muthuramalingam, Karl-Josef Dietz
1Biochemistry and Physiology of Plants, Faculty of Biology, Bielefeld University, Bielefeld, Germany. janine.koenig@uni-bielefeld.de
Abstract:
Plant cells sense, weigh and integrate various endogenous and exogenous cues in order to optimize acclimation and resource allocation. The thiol/disulfide redox network appears to be in the core of this versatile integration process. In plant cells its complexity exceeds by far that of other organisms. Recent research has elucidated the multiplicity of the diversified input elements, transmitters (thioredoxin, glutaredoxins), targets and sensors (peroxiredoxins and other peroxidases), controlled processes and final acceptors (reactive oxygen species). An additional level of thiol/disulfide regulation is achieved by introducing dynamics in time and subcompartment and complex association.
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