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Related Experiment Video

Updated: May 26, 2026

Optimized Staining and Proliferation Modeling Methods for Cell Division Monitoring using Cell Tracking Dyes
22:49

Optimized Staining and Proliferation Modeling Methods for Cell Division Monitoring using Cell Tracking Dyes

Published on: December 13, 2012

Software for precise tracking of cell proliferation.

Hiroshi Kurokawa1, Hisayori Noda, Mayu Sugiyama

  • 1Brain Science Institute, RIKEN, Wako-city, Saitama, Japan.

Biochemical and Biophysical Research Communications
|January 10, 2012
PubMed
Summary
This summary is machine-generated.

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We created TADOR, a new cell tracking software, to precisely monitor cell division and cell-cycle progression in fluorescence images. This tool overcomes common issues, enabling accurate analysis of cell behavior over time.

Area of Science:

  • Cell Biology
  • Biotechnology
  • Image Analysis

Background:

  • Accurate cell tracking is crucial for understanding cell division and cell-cycle dynamics.
  • Existing methods often struggle with signal fluctuations and morphological changes, leading to inaccuracies.

Purpose of the Study:

  • To develop and validate a novel multi-target cell tracking program, TADOR.
  • To enable precise and reliable tracking of cell division and cell-cycle progression using fluorescence imaging.

Main Methods:

  • Developed TADOR, a cell tracking program based on an active contour model.
  • Modified the active contour model to resist signal fluctuation and morphological changes.
  • Implemented backward tracing and user-interactive correction for semi-automated, off-line analysis.

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Temporal Tracking of Cell Cycle Progression Using Flow Cytometry without the Need for Synchronization
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Temporal Tracking of Cell Cycle Progression Using Flow Cytometry without the Need for Synchronization

Published on: August 16, 2015

Analysis of Cell Cycle Position in Mammalian Cells
12:19

Analysis of Cell Cycle Position in Mammalian Cells

Published on: January 21, 2012

Related Experiment Videos

Last Updated: May 26, 2026

Optimized Staining and Proliferation Modeling Methods for Cell Division Monitoring using Cell Tracking Dyes
22:49

Optimized Staining and Proliferation Modeling Methods for Cell Division Monitoring using Cell Tracking Dyes

Published on: December 13, 2012

Temporal Tracking of Cell Cycle Progression Using Flow Cytometry without the Need for Synchronization
08:52

Temporal Tracking of Cell Cycle Progression Using Flow Cytometry without the Need for Synchronization

Published on: August 16, 2015

Analysis of Cell Cycle Position in Mammalian Cells
12:19

Analysis of Cell Cycle Position in Mammalian Cells

Published on: January 21, 2012

Main Results:

  • TADOR demonstrated resistance to signal fluctuation and morphological changes.
  • The program enabled precise tracking of cell division, including cell-cycle progression.
  • Successfully applied TADOR to analyze cultured cells with fluorescently labeled nuclei over extended periods.

Conclusions:

  • TADOR is a robust and accurate tool for multi-target cell tracking.
  • The software facilitates detailed analysis of cell division and cell-cycle progression in fluorescence microscopy.
  • TADOR offers a reliable solution for researchers studying cellular dynamics.