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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
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Related Experiment Video

Updated: May 26, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

Age, weight and obesity.

Martha Apostolopoulou1, Christos Savopoulos, Konstantinos Michalakis

  • 1Internal Medicine Department, Agios Pavlos Hospital, Thessaloniki, Greece.

Maturitas
|January 10, 2012
PubMed
Summary

Overweight and obesity are rising in aging populations, increasing non-communicable disease risks. This review explores lifestyle, body composition, and other factors contributing to weight issues in older adults.

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Area of Science:

  • Gerontology
  • Public Health
  • Metabolic Disorders

Background:

  • Improved medical care and living conditions lead to longer lifespans in Western societies.
  • Escalating prevalence of overweight and obesity in the aging population is a growing public health concern.
  • A U-shaped relationship exists between body weight and mortality, indicating risks from both underweight and overweight conditions.

Purpose of the Study:

  • To examine the multifactorial contributors to overweight and obesity specifically in older adults.
  • To synthesize current knowledge on factors influencing weight status in the elderly population.
  • To identify key areas for intervention and further research regarding geriatric obesity.

Main Methods:

  • Comprehensive literature review of studies focusing on overweight and obesity in older individuals.
  • Analysis of factors including lifestyle, psychological status, physiological changes, and co-existing diseases.
  • Synthesis of evidence from various research designs to identify common themes and contributing elements.

Main Results:

  • Lifestyle factors, including diet and physical activity, play a significant role in weight management in older adults.
  • Psychological factors such as depression are associated with changes in weight.
  • Physiological changes, including alterations in body composition and endocrine function, alongside oxidative stress, contribute to weight gain.
  • Concomitant diseases and their management can also influence the weight status of elderly individuals.

Conclusions:

  • Overweight and obesity in older adults result from a complex interplay of lifestyle, psychological, physiological, and medical factors.
  • Understanding these contributing factors is crucial for developing targeted strategies to manage weight and reduce non-communicable disease risk in the aging population.
  • Further research is needed to elucidate specific mechanisms and optimize interventions for geriatric weight management.