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High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
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Published on: February 2, 2024

The genus Gelsemium: An update.

V Dutt1, S Thakur, V J Dhar

  • 1Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, Punjab, India.

Pharmacognosy Reviews
|January 10, 2012
PubMed
Summary
This summary is machine-generated.

This review explores Gelsemium species, detailing their ethnopharmacology, phytoconstituents like alkaloids and iridoids, and medicinal uses. Gelsemium elegans and Gelsemium sempervirens show potential for nervous system relaxation and anticancer activity.

Keywords:
Alkaloidsanticancergelsemiumlridoids

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Published on: February 3, 2017

Area of Science:

  • Ethnobotany and Phytochemistry
  • Pharmacology and Toxicology

Background:

  • The genus Gelsemium encompasses several species, including G. elegans, G. sempervirens, and G. rankinii.
  • These plants are recognized for both their medicinal properties and toxicity.

Purpose of the Study:

  • To provide a comprehensive review of the genus Gelsemium.
  • To summarize ethnopharmacological data, morphology, phytoconstituents, pharmacological actions, clinical studies, and toxicology.

Main Methods:

  • A systematic review of 103 references pertaining to the genus Gelsemium.
  • Compilation of data on phytochemistry, pharmacology, and clinical applications.

Main Results:

  • Alkaloids and iridoids are the primary phytoconstituents identified in Gelsemium species.
  • G. elegans and G. sempervirens are noted for their traditional use as nervous system relaxants.
  • Significant research has focused on the anticancer potential of these species.

Conclusions:

  • Gelsemium species, particularly G. elegans and G. sempervirens, hold considerable medicinal value.
  • Further research is warranted to fully elucidate the diverse biological activities and mechanisms of action of Gelsemium species.