Related Experiment Video
Updated: May 26, 2026

Reproducible Mouse Sciatic Nerve Crush and Subsequent Assessment of Regeneration by Whole Mount Muscle Analysis
Published on: February 22, 2012
Mutual information for the detection of crush
Peter Harding1, Steve Gwynne, Martyn Amos
1School of Computing, Mathematics and Digital Technology, Manchester Metropolitan University, Manchester, United Kingdom.
Abstract:
Fatal crush conditions occur in crowds with tragic frequency. Event organizers and architects are often criticised for failing to consider the causes and implications of crush, but the reality is that both the prediction and prevention of such conditions offer a significant technical challenge. Full treatment of physical force within crowd simulations is precise but often computationally expensive; the more common method of human interpretation of results is computationally "cheap" but subjective and time-consuming. This paper describes an alternative method for the analysis of crowd behaviour, which uses information theory to measure crowd disorder. We show how this technique may be easily incorporated into an existing simulation framework, and validate it against an historical event. Our results show that this method offers an effective and efficient route towards automatic detection of the onset of crush.

