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Updated: Oct 12, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Squamous-cell carcinoma and pilonidal sinus disease. Case report and review of literature]
Ciro De Martino1, Antonio Martino, Antonio Cuccuru
1Azienda Ospedaliera Regionale 'San Carlo" di Potenza, UOC di Chirurgia d'Ugenza, Potenza. ciro.de@tiscalinet.it
Abstract:
Squamous-cell carcinoma arising in a pilonidal sinus is a rare occasion. Authors report the case of a 60 years old male, with a 15 years history of recurrent pilonidal sinus disease. The patient underwent incisional biopsy, staging with total body CT, and finally radical surgery. The large wound healed by secondary intention, with a complete formation of the scar in three months. After six months, no complications or signs of recurrence were observed. Authors recommend careful inspection of the pilonidal area in all chronic and longstanding inflammatory lesions to identify promptly malignant transformation.