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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Methicillin-resistant Staphylococcus pseudintermedius isolated from canine pyoderma in North China
1Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Journal of Applied Microbiology
|January 11, 2012
Summary
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) was found in 12.7% of dogs with pyoderma in North China. The study identified two main MRSP clonal lineages, ST71 and ST5, highlighting a significant veterinary challenge.
Area of Science:
- Veterinary Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Canine pyoderma is a common skin infection.
- Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an emerging pathogen in veterinary medicine.
- Limited data exists on MRSP prevalence in China.
Purpose of the Study:
- To determine the prevalence of MRSP in dogs with pyoderma in North China.
- To characterize MRSP isolates from these dogs.
- To provide baseline data for future surveillance.
Main Methods:
- Swabs collected from 260 dogs with pyoderma.
- Phenotypic and genotypic confirmation of MRSP.
- Characterization using MLST, spa typing, SCC mec typing, antimicrobial susceptibility testing, and PFGE.
Main Results:
- MRSP was detected in 12.7% (33/260) of dogs.
- The most common MRSP genotypes were ST71-t06-II-III (66.7%) and ST5-t19 (24.2%).
- All MRSP isolates exhibited extended antimicrobial resistance.
Conclusions:
- Clinical MRSP isolates in North China belong to two major clonal lineages: ST71 and ST5.
- This is the first report of MRSP from canine pyoderma in China.
- Further surveillance is recommended to address this clinical challenge.
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