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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Methicillin-resistant Staphylococcus pseudintermedius isolated from canine pyoderma in North China

Y Wang1, J Yang, C M Logue

  • 1Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing, China.

Journal of Applied Microbiology
|January 11, 2012
PubMed
Abstract

Insights

Methicillin-resistant Staphylococcus pseudintermedius (MRSP) was found in 12.7% of dogs with pyoderma in North China. The study identified two main MRSP clonal lineages, ST71 and ST5, highlighting a significant veterinary challenge.

Area of Science:

  • Veterinary Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Canine pyoderma is a common skin infection.
  • Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an emerging pathogen in veterinary medicine.
  • Limited data exists on MRSP prevalence in China.

Purpose of the Study:

  • To determine the prevalence of MRSP in dogs with pyoderma in North China.
  • To characterize MRSP isolates from these dogs.
  • To provide baseline data for future surveillance.

Main Methods:

  • Swabs collected from 260 dogs with pyoderma.
  • Phenotypic and genotypic confirmation of MRSP.
  • Characterization using MLST, spa typing, SCC mec typing, antimicrobial susceptibility testing, and PFGE.

Main Results:

  • MRSP was detected in 12.7% (33/260) of dogs.
  • The most common MRSP genotypes were ST71-t06-II-III (66.7%) and ST5-t19 (24.2%).
  • All MRSP isolates exhibited extended antimicrobial resistance.

Conclusions:

  • Clinical MRSP isolates in North China belong to two major clonal lineages: ST71 and ST5.
  • This is the first report of MRSP from canine pyoderma in China.
  • Further surveillance is recommended to address this clinical challenge.

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