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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Custom vs conventional PRK: a prospective, randomized, contralateral eye comparison of postoperative visual function.

Mark D Mifflin1, Bryndon B Hatch, Shameema Sikder

  • 1University of Utah, Department of Ophthalmology and Visual Sciences, Salt Lake City, Utah, USA. mark.mifflin@hsc.utah.edu

Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|January 11, 2012
PubMed
Summary

Custom and conventional photorefractive keratectomy (PRK) offer safe and effective vision correction. While conventional PRK induced more coma, both methods yielded excellent visual acuity and contrast sensitivity.

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Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Corneal Surgery

Background:

  • Photorefractive keratectomy (PRK) is a common refractive surgery procedure.
  • Advancements in laser technology allow for customized treatment plans.
  • Comparing custom vs. conventional PRK is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To compare the visual outcomes of VISX S4 custom photorefractive keratectomy (PRK) versus VISX S4 conventional PRK.
  • To evaluate differences in visual acuity, contrast sensitivity, and higher-order aberrations between the two PRK methods.

Main Methods:

  • A randomized, prospective, contralateral eye study involving 40 patients (80 eyes).
  • Eyes were assigned to either custom or conventional PRK treatment.
  • Primary outcome measures included uncorrected and corrected distance visual acuity, contrast sensitivity, and higher-order aberrations (RMS).

Main Results:

  • No significant difference in uncorrected or corrected distance visual acuity between custom and conventional PRK at 6 months.
  • Both groups showed increased higher-order aberrations and spherical aberration post-surgery.
  • Conventional PRK induced significantly more coma compared to custom PRK, but this did not impact clinical outcomes.

Conclusions:

  • Both custom and conventional PRK using VISX S4 are safe and effective for vision correction.
  • Excellent visual acuity and contrast sensitivity were achieved with both techniques.
  • Custom PRK may offer an advantage in reducing induced coma compared to conventional PRK.