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Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
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Neglect severity after left and right brain damage.

Julia Suchan1, Chris Rorden, Hans-Otto Karnath

  • 1Center of Neurology, Division of Neuropsychology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

Neuropsychologia
|January 11, 2012
PubMed
Summary
This summary is machine-generated.

Unilateral spatial neglect is less frequent after left brain damage but, when present, its severity is similar to that seen after right brain injury. This study validated a new measurement tool for assessing neglect severity in left brain damage patients.

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Area of Science:

  • Neuroscience
  • Neurology
  • Cognitive Psychology

Background:

  • Unilateral spatial neglect (USN) is a common consequence of brain damage, typically following right hemisphere lesions.
  • USN after left hemisphere damage is considered less frequent and less severe than after right hemisphere damage.

Purpose of the Study:

  • To validate the Center of Cancellation (CoC) measure for assessing USN severity in patients with acute left brain damage.
  • To compare the severity of USN in patients with acute left brain damage versus acute right brain damage.

Main Methods:

  • The Center of Cancellation (CoC) measure was applied to 48 patients with left-sided stroke.
  • Cancellation tasks (Bells Test, Letter Cancellation Task) were used to calculate the CoC score.
  • CoC scores for left brain damage patients were compared to established data for right brain damage patients.

Main Results:

  • Specific CoC score thresholds were identified to indicate neglect behavior in acute left brain damage patients.
  • The severity of USN in patients with acute left brain damage was found to be similar to that in patients with acute right brain damage.

Conclusions:

  • The CoC measure is a valid tool for assessing USN severity in acute left brain damage.
  • Contrary to assumptions, USN is of comparable severity regardless of whether the lesion is in the left or right hemisphere.