Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of a New Riluzole-Based Compound VA945 on Sodium and Potassium Conductances Expressed by SH-SY5Y- Derived Neurons.

Journal of neurochemistry·2025
Same author

Fungal Planet description sheets: 1697-1780.

Fungal systematics and evolution·2025
Same author

Watt-level single-frequency optical parametric oscillator around 2 µm.

Optics letters·2024
Same author

Dragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy.

Cardiovascular and interventional radiology·2022
Same author

Hyaluronan derivatives bearing variable densities of ferulic acid residues.

Journal of materials chemistry. B·2020
Same author

Evidence on the need for an integrated approach to the management of diabetes: the surgical perspective.

Translational medicine @ UniSa·2020

Related Experiment Video

Updated: May 26, 2026

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
03:53

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Published on: March 15, 2024

Primary amputation: is there still a place for it?

F Setacci1, P Sirignano, G De Donato

  • 1Department of Surgery, Vascular and Endovascular Surgery Unit, University of Siena, Siena, Italy. setacci2@unisi.it

The Journal of Cardiovascular Surgery
|January 11, 2012
PubMed
Summary

Diabetic foot (DF) amputations remain high despite advanced vascular treatments. Aggressive revascularization

More Related Videos

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
08:11

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation

Published on: June 13, 2025

Orthotopic Hind Limb Transplantation in the Mouse
07:15

Orthotopic Hind Limb Transplantation in the Mouse

Published on: February 12, 2016

Related Experiment Videos

Last Updated: May 26, 2026

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
03:53

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Published on: March 15, 2024

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
08:11

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation

Published on: June 13, 2025

Orthotopic Hind Limb Transplantation in the Mouse
07:15

Orthotopic Hind Limb Transplantation in the Mouse

Published on: February 12, 2016

Area of Science:

  • Vascular Surgery
  • Diabetology
  • Podiatry

Background:

  • Diabetic foot (DF) poses a significant challenge, with amputation rates increasing.
  • Despite advances, limb salvage remains a concern, particularly in older populations.
  • Primary amputation carries a high mortality rate.

Purpose of the Study:

  • To evaluate the effectiveness of aggressive revascularization in limb salvage for diabetic foot patients.
  • To discuss current therapeutic options for obstructive vascular pathology in DF.
  • To analyze amputation trends and outcomes in the United States.

Main Methods:

  • Review of open revascularization and endovascular techniques.
  • Analysis of amputation rates and mortality data.
  • Discussion of surgical and non-surgical interventions for vascular pathology.

Main Results:

  • Amputation rates have risen, especially in patients over 85.
  • Primary amputation is associated with high mortality.
  • Various revascularization techniques are available, but their impact on limb salvage is debated.

Conclusions:

  • Amputation is increasingly viewed as a last resort due to available limb-preservation techniques.
  • Effective management of diabetic foot requires a multidisciplinary approach.
  • Further research is needed to optimize revascularization strategies for limb salvage.