Related Experiment Video
Updated: May 26, 2026
10:41
Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
Published on: June 3, 2021
Acute epidural spinal hemorrhage from vasculitis: resolution with immunosuppression
Jeffrey T Jacob1, Shota Tanaka, Christopher P Wood
1Department of Neurologic Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. jacob.jeffrey@mayo.edu
Neurocritical Care
|January 11, 2012
Summary
Spinal vasculitis, a rare condition, can cause severe back pain. Immunosuppression therapy, like cyclophosphamide, showed significant improvement in a patient with this condition.
Area of Science:
- Neurology
- Rheumatology
- Radiology
Background:
- Angiographic vasculitis of the spine is a rare condition.
- This case report reviews the literature on spinal vasculitis.
- Immunosuppression is explored as a primary treatment modality.
Observation:
- A 61-year-old female presented with acute onset back pain and headache.
- Diagnostic work-up revealed acute spinal epidural hemorrhage.
- Angiographic findings confirmed spinal vasculitis.
Findings:
- Treatment with cyclophosphamide, an immunosuppressive agent, led to clinical improvement.
- Radiographic evidence also demonstrated improvement following immunosuppression.
- The patient experienced resolution of symptoms and disease markers.
Implications:
- Immunomodulating therapy is a viable treatment option for spinal vasculitis.
- Early diagnosis and treatment can lead to improved clinical outcomes.
- This approach may potentially lead to disease resolution in select patients.
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