Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Jaundice01:25

Jaundice

Jaundice, or icterus, is the yellow discoloration of the skin, sclerae, and mucous membranes. It happens when plasma bilirubin levels rise above 2.5-3 mg/dL, leading to bilirubin deposition in tissue.Bilirubin is a byproduct of hemoglobin degradation. In macrophages, hemoglobin breaks down into globin and heme. Globin is converted into amino acids, while heme is turned into biliverdin by heme oxygenase, which is then reduced to unconjugated bilirubin by biliverdin reductase.Unconjugated...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consensus-based Guideline on tinea capitis.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same author

S1 Guideline on Infected Interdigital Intertrigo (also called Gram-Negative Toe Web Infection).

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same author

S1-Leitlinie Onychomykose.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2023
Same author

S1 Guideline onychomycosis.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2023
Same author

Das Potenzial der Telemedizin für die dermatologische Versorgung pädiatrischer Patienten in Deutschland.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2023
Same author

The potential of telemedicine for dermatological care of pediatric patients in Germany.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2023

Related Experiment Video

Updated: May 26, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

[Pityriasis versicolor].

Dietrich Abeck1

  • 1professorabeck@mytum.de

Medizinische Monatsschrift Fur Pharmazeuten
|January 12, 2012
PubMed
Summary

Malassezia yeast infections are common skin issues that still present challenges in understanding their causes and developing effective prevention and treatment strategies.

Area of Science:

  • Dermatology
  • Mycology
  • Infectious Diseases

Background:

  • Superficial fungal infections caused by Malassezia yeasts are prevalent worldwide.
  • Despite their commonality, significant knowledge gaps persist regarding pathogenesis and optimal therapeutic interventions.
  • Current prevention and treatment strategies for Malassezia-related conditions require further investigation and refinement.

Purpose of the Study:

  • To address the unresolved questions in the pathogenesis of Malassezia yeast infections.
  • To explore and evaluate novel therapeutic approaches for managing these infections.
  • To identify effective strategies for the prevention of recurrent or persistent Malassezia-related skin conditions.

Main Methods:

  • Review of existing literature on Malassezia yeast biology and clinical manifestations.

Related Experiment Videos

Last Updated: May 26, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

  • Analysis of current treatment protocols and their efficacy.
  • Exploration of potential targets for antifungal therapies and preventative measures.

    • Main Results:

    • Identification of key pathogenetic pathways involved in Malassezia-induced skin conditions.
    • Evaluation of the limitations of existing antifungal treatments.
    • Highlighting the need for targeted prevention strategies based on yeast-host interactions.

    Conclusions:

    • Further research is crucial to fully elucidate the complex pathogenesis of Malassezia infections.
    • Development of innovative and effective therapeutic and preventive strategies is warranted.
    • A comprehensive understanding of Malassezia yeast biology is essential for improved patient outcomes.