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Updated: May 26, 2026
Isolation and Activation of Murine Lymphocytes
Published on: October 30, 2016
[Study on the activated fraction with proliferation and apoptosis effect on T lymphocyte of Celastrus aculeatus]
Pei-Hong Chen1, Zong-Bao Ding, Yang Xie
1School of Chinese Medicine, Southern Medical University, Guangzhou 510515, China. cph1216@163.com
Objective:
To screen the activated fraction from Celastrus aculeatus and study its effect on T lymphocyte apoptosis.
Methods:
Different polarity fractions were isolated from Celastrus aculeatus extract. Flow Cytometry method was used to detect apoptosis ratio of the active fractions.
Results:
Different fractions extract from Celastrus aculeatus and GSF-A could significantly inhibit T lymphocyte proliferation and induce T lymphocyte apoptosis.
Conclusion:
The activated fractions isolated from Celastrus aculeatus have anti-inflammatory effect. Its mechanism may be related to the apoptosis effect on T lymphocyte.
