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Related Concept Videos

Precipitation and Co-precipitation01:17

Precipitation and Co-precipitation

Precipitation and coprecipitation methods can be used to separate a mixture of ions in a solution. In qualitative inorganic analysis, ions that form sparingly soluble precipitates with the same reagent are separated based on the differences in solubility products. For example, consider the separation of Cu(II) and Fe(II) ions by precipitation as insoluble sulfides. First, copper(II) sulfide is precipitated by the addition of acidic H2S, where the dissociation of H2S is suppressed. Adding H2S...
Microbes and Other Elemental Cycles01:24

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Microbial activity plays a pivotal role in the biogeochemical cycling of iron and manganese, especially at the redox gradients characteristic of stratified aquatic environments. These cycles are driven by microbial transformations between oxidized and reduced forms of the metals, allowing organisms to exploit them for metabolic energy and structural purposes.Iron Cycling Across Redox GradientsIn neutral, oxygen-rich surface waters, iron is predominantly found in its oxidized, insoluble ferric...
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A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
The Periodic Table and Organismal Elements00:57

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OverviewElements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally-occurring, and fewer still are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.The Periodic Table Provides Information...
Sulfur Assimilation01:20

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Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to become...
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Updated: May 26, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
03:55

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Published on: June 27, 2022

Ferric Iron and Cobalt (III) compounds to safely decrease hydrogen sulfide in the body?

Andry Van de Louw, Philippe Haouzi

    Antioxidants & Redox Signaling
    |January 12, 2012
    PubMed
    Summary
    This summary is machine-generated.

    Vitamin B12 (vit.B12) and low methemoglobin (MetHb) levels can safely modulate endogenous hydrogen sulfide (H2S) concentrations in vivo. This approach offers a novel method to investigate H2S roles in human health and disease.

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    Quantifiable and Inexpensive Cell-Free Fluorescent Method to Confirm the Ability of Novel Compounds to Chelate Iron

    Published on: February 23, 2024

    Area of Science:

    • Biochemistry
    • Physiology
    • Pharmacology

    Background:

    • Investigating endogenous hydrogen sulfide (H2S) roles in systemic inflammation and hypoxia requires safe human application methods.
    • Vitamin B12 (vit.B12) and low methemoglobin (MetHb) levels are explored as tools to affect H2S concentration.

    Discussion:

    • Hydroxocobalamin (a form of vit.B12) was detected in rat tissues after intravenous administration.
    • Exogenous H2S degradation was significantly higher in rats treated with vit.B12.
    • Hydroxocobalamin rapidly decreased H2S in vitro, and MetHb prevented H2S-induced hyperventilation in vivo.

    Key Insights:

    • In vitro, hydroxocobalamin (100 μM) reduced equimolar H2S by 80% within 2 minutes.
    • 3-5% MetHb prevented H2S-induced hyperventilation and reduced exogenous H2S by 25-40 μM within 30 seconds.
    • These findings suggest vit.B12 and MetHb can be used to safely test endogenous H2S roles in vivo.

    Outlook:

    • Further research is warranted to validate the safety and efficacy of this approach in human clinical settings.
    • This method could provide new insights into H2S involvement in various pathological conditions.
    • Potential therapeutic applications targeting H2S pathways may emerge from this research.