Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Treatment Resistent Cancers

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Exploring cochlear implantation and quality of life in pediatric recipients with autism spectrum disorder.

International journal of pediatric otorhinolaryngology·2026

Same author

The Key Word Is Trust: Hearing Healthcare Experiences Among Black Adults Who Meet Audiometric Candidacy Criteria for Cochlear Implantation.

Ear and hearing·2025

Same author

Development of a Mobile App to Support Head and Neck Cancer Caregiving: Mixed Methods Study.

JMIR cancer·2025

Same author

Clinicopathologic Factors and Outcomes of Neuroendocrine Carcinoma in the Oropharynx: An Analysis of the National Cancer Database (NCDB).

Head & neck·2025

Same author

HPV-Associated Oropharyngeal Cancer in Patients With Chronic Lymphocytic Leukemia.

The Laryngoscope·2025

Same author

Combined Mastoidectomy and Middle Fossa Craniotomy for Tegmen Defect Repair: Long-Term Outcomes Using a Multidisciplinary Approach.

Operative neurosurgery (Hagerstown, Md.)·2025

Search research articles

Related Experiment Video

Updated: May 25, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

Well differentiated thyroid carcinoma: current treatment.

J Kenneth Byrd¹, Robert J Yawn, Christina S T Wilhoit

¹Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425-5500, USA. byrdj@musc.edu

Current Treatment Options in Oncology

|January 12, 2012

Summary

This summary is machine-generated.

Well differentiated thyroid carcinoma (WDTC) management involves surgical options like total thyroidectomy for larger papillary thyroid carcinomas (PTC) and radioactive iodine therapy to reduce recurrence.

More Related Videos

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Published on: June 2, 2023

Related Experiment Videos

Last Updated: May 25, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Published on: June 2, 2023

Area of Science:

Oncology
Endocrinology
Surgical Oncology

Background:

Well differentiated thyroid carcinoma (WDTC) is a common malignancy with a generally high survival rate.
Papillary thyroid carcinoma (PTC) represents a significant subset of WDTC.

Purpose of the Study:

To outline current management strategies for well differentiated thyroid carcinoma.
To detail surgical and post-operative treatment recommendations for PTC.

Main Methods:

Review of established clinical guidelines and literature for WDTC and PTC treatment.
Surgical management recommendations based on tumor size and prognostic factors.
Indications for radioactive iodine (131I) ablation and TSH suppression therapy.

Main Results:

Total thyroidectomy is recommended for PTC greater than 1 cm.
Thyroid lobectomy may suffice for smaller, unifocal PTC without adverse prognostic factors.
Neck dissections are indicated for nodal metastases.
Radioactive iodine (131I) ablation and TSH suppression aid in locoregional control and recurrence reduction.

Conclusions:

Optimal WDTC management integrates surgical intervention with adjuvant therapies.
Personalized treatment approaches are crucial for papillary thyroid carcinoma based on individual risk factors.
Post-operative strategies aim to minimize recurrence and improve long-term outcomes.