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Extremely high values of CA 19-9 in liver hydatidosis and frank biliary rupture
Jose M Ramia1, Roberto De la Plaza, Jose Quiñones
1Hospital De Guadalajara, Department of Surgery, Madrid, Spain. jose_ramia@hotmail.com
Insights
Huge elevations in carbohydrate antigen 19-9 (CA 19-9) can occur in obstructive jaundice due to liver hydatidosis. This study explores the relationship between this parasitic liver disease and elevated CA 19-9 levels.
Area of Science:
- Hepatology
- Parasitology
- Clinical Chemistry
Background:
- Elevated carbohydrate antigen 19-9 (CA 19-9) is common in jaundiced patients with benign biliary diseases.
- The exact cause of this elevation remains unclear.
- Liver hydatidosis with intrabiliary rupture can cause obstructive jaundice.
Abstract:
Elevation of carbohydrate antigen 19-9 has been observed in jaundiced patients with benign biliary tract diseases. No clear answer has explained that relationship. Patients with liver hydatidosis and frank intrabiliary rupture could present obstructive jaundice due to the presence of liver cyst material in the bile duct. We present two cases of huge elevation of carbohydrate antigen 19-9 in jaundiced patients with liver hydatidosis and biliocystic communication, and we assess the different theories presented in the medical literature today.
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