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Economic evaluation of the national immunization program of rotavirus vaccination for children in Korea

Hye-Young Kang1, Ki Hwan Kim, Ji Hong Kim

  • 1Yonsei University, College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Incheon, Korea.

Asia-Pacific Journal of Public Health
|January 12, 2012
PubMed

Insights

Rotavirus vaccination is a cost-effective strategy for Korea. It significantly reduces symptomatic cases and disease burden, making it a valuable public health intervention.

Area of Science:

  • Public Health
  • Health Economics
  • Vaccinology

Background:

  • Rotavirus diarrhea poses a significant health and economic burden.
  • Developing an evidence-based national immunization program is crucial for disease prevention.

Purpose of the Study:

  • To assess the cost-effectiveness of rotavirus vaccination in Korea.
  • To inform the development of a national immunization program.

Main Methods:

  • A Markov model was utilized to compare vaccination versus no vaccination.
  • Korea-specific data on rotavirus epidemiology and economic burden were incorporated.
  • Efficacy data from a clinical trial of RotaTeq® were used.

Main Results:

  • Universal rotavirus vaccination is projected to prevent 181,238 symptomatic cases (63.2% reduction) over 5 years.
  • The cost per case averted was estimated at 375,620 Korean Won (KW).
  • The breakeven vaccine price was calculated to be 56,061 KW.

Conclusions:

  • Rotavirus vaccination substantially reduces the disease burden in Korea.
  • Universal rotavirus vaccination is a cost-effective public health strategy.

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