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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

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Cortical hyperexcitability in migraine and aversion to patterns.

Sm Haigh¹, O Karanovic, F Wilkinson

¹Department of Psychology, University of Essex, UK.

Cephalalgia : an International Journal of Headache

|January 12, 2012

Summary

Migraine patients show greater aversion to visual stimuli than controls. This aversion is not linked to the cortical hyperexcitability seen in photosensitive epilepsy.

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Published on: May 12, 2019

Area of Science:

Neuroscience
Ophthalmology
Neurology

Background:

Migraine patients exhibit aversion to visual stimuli like flicker and patterns.
This aversion is debated to stem from cortical hyperexcitability, similar to photosensitive epilepsy.
Specific grating patterns can be epileptogenic in photosensitive epilepsy, depending on movement.

Purpose of the Study:

To compare visual grating aversion in migraineurs and controls.
To investigate if migraine aversion is linked to photosensitive epilepsy mechanisms.

Main Methods:

Aversion thresholds to static, vibrating, and drifting gratings were measured in migraineurs and controls.
Contrast levels were gradually increased until discomfort was reported.

Main Results:

Migraineurs had significantly lower aversion thresholds than controls.
Static gratings were less aversive than moving gratings for both groups.
Drifting gratings were more aversive than vibrating gratings.

Conclusions:

Migraineurs' visual aversion is not explained by cortical hyperexcitability seen in photosensitive epilepsy.
The study differentiates migraine visual sensitivity from epilepsy-related visual triggers.