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Effect of clindamycin on adherence of coagulase-negative Staphylococcus to surgical nets
M R Gismondo1, G Chisari, A M Lo Bue
1Institute of Microbiology, University of Catania, Italy.
Il Giornale Di Chirurgia
|April 1, 1990
Abstract:
The authors studied the effect that a subinhibitory concentration of Clindamycin has on adherence of coagulase negative S. epidermidis to surgical nets. Clindamycin, as expected, interferes with the adhesivity to the nets of coagulase-negative S. epidermidis slime producing when sub-MICs are used. The documentation obtained by scanning electron microscope, after treatment of the strains with doses of Clindamycin equal to 1/6 of the MIC after 3 and 6 hours, confirms the anti-adherent effect of the antibiotic.