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Diagnostic indicators for peptic ulcer perforation at a tertiary care hospital in Thailand

Chutikarn Suriya1, Nongyao Kasatpibal, Wipada Kunaviktikul

  • 1Clinical Epidemiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Clinical and Experimental Gastroenterology
|January 12, 2012
PubMed

Insights

Early detection of peptic ulcer perforation in Thailand is crucial. Key indicators include intense abdominal pain, tenderness, guarding, X-ray findings of free air, and hospital referral, aiding timely medical intervention.

Area of Science:

  • Gastroenterology
  • Surgical Diagnostics
  • Public Health Epidemiology

Background:

  • Limited data exists on diagnostic indicators for peptic ulcer perforation in Thailand.
  • Delayed diagnosis and treatment of peptic ulcers can be fatal.

Purpose of the Study:

  • To identify key diagnostic indicators for peptic ulcer perforation.
  • To improve early detection and patient outcomes in Thailand.

Main Methods:

  • A cohort study involving 1290 peptic ulcer patients (aged ≥15) in a Thai tertiary hospital (2005-2009).
  • Analysis of patient profiles, symptoms, lab results, and radiological findings using exponential risk regression.
  • Utilized Stata(®) statistical software, version 11 for analysis.

Main Results:

  • 57% of patients had perforated peptic ulcer.
  • Significant indicators identified: intense abdominal pain (RR=1.53), tenderness (RR=1.94), guarding (RR=1.52), X-ray showing free air (RR=2.80), and referral from other hospitals (RR=1.37).

Conclusions:

  • Five key diagnostic indicators for monitoring peptic ulcer perforation were identified.
  • Enhancing diagnostic capabilities can improve outcomes for patients with perforated peptic ulcers.
Abstract

Keywords:
Thailanddiagnostic indicatorpeptic ulcer perforation

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