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Protein Networks02:26

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Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

Connecting the dots between PubMed abstracts.

M Shahriar Hossain1, Joseph Gresock, Yvette Edmonds

  • 1Department of Computer Science, Virginia Tech, Blacksburg, Virginia, United States of America. msh@vt.edu

Plos One
|January 12, 2012
PubMed
Summary
This summary is machine-generated.

This study introduces a storytelling algorithm to connect fragmented biological research across publications. It helps scientists discover new connections and generate hypotheses from vast amounts of literature.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Systems Biology

Background:

  • Vast amounts of biological research are published across diverse journals.
  • Integrating information from multiple publications is crucial for understanding complex biological systems.
  • Unraveling relationships between extracellular inputs and molecular responses requires synthesizing diverse findings.

Purpose of the Study:

  • To develop an automated approach for biological knowledge discovery from PubMed abstracts.
  • To create a "storytelling" algorithm for connecting disparate scientific literature.
  • To facilitate hypothesis generation and exploration of connections within large biological knowledge bases.

Main Methods:

  • An automated storytelling algorithm was developed to identify chains of publications linking a start and end abstract.
  • The algorithm identifies intermediate publications with significant content similarity.
  • Coherence and overlap filters were designed as post-processing steps to ensure story integrity.

Main Results:

  • The algorithm successfully generated "stories" connecting publications with little initial overlap.
  • Case studies demonstrated applications in many-one, many-many, and one-to-one relationship discoveries.
  • The pipeline significantly narrowed down relevant documents from hundreds of thousands to approximately one hundred stories.

Conclusions:

  • The storytelling algorithm serves as a valuable discovery aid for hypothesis generation.
  • It enables efficient exploration of connections within large, unstructured biological knowledge bases.
  • This approach aids scientists in focusing their research by connecting disparate findings.