Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sugars as Energy Storage Molecules01:10

Sugars as Energy Storage Molecules

Sugar (a simple carbohydrate) metabolism (chemical reactions) is a classic example of the many cellular processes that use and produce energy. Living things consume sugar as a major energy source because sugar molecules have considerable energy stored within their bonds. Consumed carbohydrates have their origins in photosynthesizing organisms like plants. During photosynthesis, plants use the energy of sunlight to convert carbon dioxide gas into sugar molecules, like glucose. Because this...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anti-cancer effect of a novel photodynamic therapy using glucose-linked chlorin e6 conjugated trastuzumab for HER2-positive gastrointestinal cancers.

PloS one·2026
Same author

Pt(II) and Pd(II) complexes bearing 1,10-phenanthroline-based ligands: Distinct binding modes to DNA and anticancer activities.

Journal of inorganic biochemistry·2026
Same author

Optimization of bulkiness/dynamicity and pH utilizing N,N'-bis(5,6,7-trimethoxy-2-quinolylmethyl)-N,N'-dialkylethylenediamines as a Cd<sup>2+</sup>-specific fluorescent sensor.

Journal of inorganic biochemistry·2025
Same author

NMR investigation on the non-enzymatic breakdown of the glucosinolate sinigrin and its acetylated derivative by copper ions.

Journal of inorganic biochemistry·2025
Same author

Antitumor effects of a novel glucose-conjugated bacteriochlorin for photodynamic therapy.

Scientific reports·2025
Same author

Doubly Linked Azulene Dimer: A Novel Non-benzenoid Isomer of Perylene.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025

Related Experiment Video

Updated: May 25, 2026

Self-reporting Scaffolds for 3-Dimensional Cell Culture
14:49

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

Development of sugar-based materials for biological devices.

Yuji Mikata1, Shigenobu Yano

  • 1KYOUSEI Science Center, Nara Women's University, Kitauoyanishimachi, Nara 630-8506, Japan. mikata@cc.nara-wu.ac.jp

Current Topics in Medicinal Chemistry
|January 13, 2012
PubMed
Summary

Newly developed sugar-based ligands and their metal complexes show controlled biological activity. The carbohydrate structure influences the metal center

More Related Videos

Bridging the Bio-Electronic Interface with Biofabrication
16:38

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications
05:20

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications

Published on: May 31, 2018

Related Experiment Videos

Last Updated: May 25, 2026

Self-reporting Scaffolds for 3-Dimensional Cell Culture
14:49

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

Bridging the Bio-Electronic Interface with Biofabrication
16:38

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications
05:20

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications

Published on: May 31, 2018

Area of Science:

  • Coordination Chemistry
  • Carbohydrate Chemistry
  • Medicinal Chemistry

Background:

  • Metal complexes are crucial in various applications, including medicine.
  • Ligand design significantly impacts complex properties and function.
  • Sugar-based ligands offer unique stereochemical and biological properties.

Purpose of the Study:

  • To review recent advancements in sugar-based ligands and their metal complexes.
  • To highlight the influence of carbohydrate moieties on metal complex stereochemistry.
  • To discuss the control of biological activity through ligand design.

Main Methods:

  • Synthesis of novel sugar-based ligands.
  • Coordination of ligands with various metal centers.
  • Characterization of metal complexes (e.g., X-ray crystallography, spectroscopy).
  • Evaluation of biological activities of the complexes.

Main Results:

  • Developed novel sugar-based ligands with tunable properties.
  • Demonstrated that carbohydrate structure dictates stereochemistry around the metal center.
  • Established a correlation between ligand structure and the biological activity of metal complexes.
  • Showcased potential therapeutic applications of these metal complexes.

Conclusions:

  • Sugar-based ligands provide a versatile platform for designing metal complexes.
  • Stereochemical control afforded by carbohydrate moieties is key to modulating biological effects.
  • These findings pave the way for developing new metallodrugs with enhanced efficacy and specificity.