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Related Concept Videos

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Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Related Experiment Video

Updated: May 25, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

Copeptin in aneurysmal subarachnoid hemorrhage.

Rafael J Tamargo1

  • 1Department of Neurosurgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, 600 N, Wolfe Street, Meyer 8-181, Baltimore, MD 21287, USA. rtamarg@jhmi.edu

Critical Care (London, England)
|January 13, 2012
PubMed
Summary

Elevated copeptin levels in patients with aneurysmal subarachnoid hemorrhage (SAH) indicate a higher risk of vasospasm and poor outcomes. Further research into copeptin

Area of Science:

  • Neurology
  • Biochemistry

Background:

  • Copeptin is a stable biomarker derived from the vasopressin precursor.
  • Aneurysmal subarachnoid hemorrhage (SAH) is a critical neurological condition with significant morbidity and mortality.

Purpose of the Study:

  • To investigate the correlation between serum copeptin levels and clinical outcomes in patients with aneurysmal SAH.
  • To explore the prognostic value of copeptin in SAH management.

Main Methods:

  • Serum copeptin levels were measured in patients diagnosed with aneurysmal SAH.
  • Correlation analysis was performed between copeptin levels and outcomes such as vasospasm, mortality, and functional status.

Main Results:

  • Elevated serum copeptin levels were significantly associated with the presence of vasospasm.

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Related Experiment Videos

Last Updated: May 25, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
10:34

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

  • Higher copeptin levels correlated with increased inpatient mortality, 1-year mortality, and poor functional outcomes at 1 year post-SAH.

    • Conclusions:

    • Serum copeptin is a promising biomarker for predicting outcomes in aneurysmal SAH.
    • Further investigation into the clinical utility of copeptin in SAH patient management is warranted.