Synthesis of iron nanoparticles from hemoglobin and myoglobin
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Updated: May 25, 2026

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
Published on: December 13, 2016
Arshad S Sayyad1, Kaushik Balakrishnan, Lijie Ci
1Department of Chemistry, Rice University, Houston, TX 77005, USA.
Abstract:
Stable iron nanoparticles have been synthesized from naturally occurring and abundant Fe-containing bio-precursors, namely hemoglobin and myoglobin. The formation of stable iron nanoparticles was achieved through a one-pot, single-phase chemical reduction approach. The reduction of iron ions present in the bio-precursors was carried out at room temperature and avoids the use of harsh chemical reagents. The size distribution of the product falls into the narrow 2-5 nm range and the particles were found to be crystalline. This method can be a valuable synthetic approach for producing bio-conjugated nanoparticle systems for biological applications.
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