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Related Experiment Video

Updated: May 25, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

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Radiosurgery for brain metastases.

Douglas Kondziolka1, John C Flickinger, L Dade Lunsford

  • 1Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA. kondds@upmc.edu

Progress in Neurological Surgery
|January 13, 2012
PubMed
Summary
This summary is machine-generated.

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Stereotactic radiosurgery offers survival and local tumor control benefits for brain metastases. This minimally invasive option is effective and safe within a multidisciplinary management approach.

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Oncology

Background:

  • Brain metastases require multidisciplinary management.
  • Stereotactic radiosurgery (SRS) is an evolving treatment modality.
  • Evidence supporting SRS in brain metastases management is growing.

Purpose of the Study:

  • To review the current literature on stereotactic radiosurgery for brain metastases.
  • To focus on evidence addressing key management questions.
  • To evaluate the role of SRS alongside other treatment modalities.

Main Methods:

  • Literature review of retrospective case series, matched cohort studies, and randomized trials.
  • Analysis of the 2009 Guidelines project of the American Association of Neurological Surgeons/Congress of Neurological Surgeons (AANS/CNS).

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Stereotactic Radiosurgery for Gynecologic Cancer
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Main Results:

  • Stereotactic radiosurgery demonstrates significant survival and local tumor control benefits.
  • SRS is a safe and effective minimally invasive treatment option.
  • Randomized trials often include diverse tumor histologies, potentially limiting applicability to specific tumor types.

Conclusions:

  • Stereotactic radiosurgery is a valuable component of multidisciplinary brain metastases care.
  • The evidence supports SRS as an effective and safe treatment for brain metastases.
  • Further research may be needed to clarify SRS efficacy in specific tumor histologies.