Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 25, 2026

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
11:24

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

Radiosurgery after craniotomy.

David Mathieu1

  • 1Division of Neurosurgery/Neuro-Oncology, Department of Surgery, Université de Sherbrooke, Sherbrooke, QC, Canada. david.mathieu@usherbrooke.ca

Progress in Neurological Surgery
|January 13, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dose De-escalation in Stereotactic Radiosurgery for Melanoma Brain Metastases in Patients on Concurrent Immunotherapy or Targeted Therapy: A Multicenter Experience.

Neurosurgery·2026
Same author

Volume-Staged Stereotactic Radiosurgery in Pediatric Patients With Large Brain Arteriovenous Malformations: An International, Multicenter Study.

Neurosurgery·2026
Same author

Role of radiosurgical thalamotomy in the management for essential tremor: evidence from an international multi-institutional study.

Journal of neurology·2026
Same author

Efficacy and safety profile of volume-staged stereotactic radiosurgery for ruptured, large pediatric arteriovenous malformations: a multicenter cohort analysis.

Journal of neurosurgery. Pediatrics·2026
Same author

Active surveillance versus stereotactic radiosurgery for Koos grade I and II vestibular schwannoma in patients aged 60 years or older.

Journal of neurosurgery·2026
Same author

Safety and effectiveness of stereotactic radiosurgery for larger hemangioblastomas (>2cc): A multi-center retrospective study.

PloS one·2026

Adjuvant radiosurgery after craniotomy offers an alternative to whole-brain radiation therapy, potentially reducing neurotoxicity while maintaining local tumor control. Further research is needed to optimize patient selection and treatment parameters for this emerging technique.

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Oncology

Background:

  • Adjuvant irradiation of the resection cavity after craniotomy is an emerging stereotactic radiosurgery application.
  • This approach aims to mitigate the long-term neurotoxicity associated with whole-brain radiation therapy.
  • Retrospective studies suggest comparable local control rates to conventional methods.

Purpose of the Study:

  • To evaluate the efficacy and safety of adjuvant tumor bed radiosurgery.
  • To identify optimal patient candidates for this treatment modality.
  • To address current controversies regarding treatment parameters.

Main Methods:

  • Review of retrospective series on adjuvant radiosurgery post-craniotomy.
  • Analysis of local control rates and toxicity profiles.

More Related Videos

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

A Craniotomy Surgery Procedure for Chronic Brain Imaging
09:25

A Craniotomy Surgery Procedure for Chronic Brain Imaging

Published on: February 15, 2008

Related Experiment Videos

Last Updated: May 25, 2026

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
11:24

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

A Craniotomy Surgery Procedure for Chronic Brain Imaging
09:25

A Craniotomy Surgery Procedure for Chronic Brain Imaging

Published on: February 15, 2008

  • Exploration of treatment variables including timing, irradiated volume, and radiation dose.

    • Main Results:

    • Adjuvant radiosurgery appears to provide comparable local control rates.
    • The technique is proposed as a method to avoid whole-brain radiation therapy-induced neurotoxicity.
    • Optimal patient selection and treatment parameters remain under investigation.

    Conclusions:

    • Adjuvant tumor bed radiosurgery is a promising technique for selected patients.
    • Further research is essential to define optimal treatment protocols and patient selection criteria.
    • Key areas for future study include optimal timing, treatment volume, and radiation dosage.