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Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...

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Updated: May 25, 2026

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
09:57

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

Post-migration screening for active tuberculosis in Victoria, Australia.

M Flynn1, L Brown, A Tesfai

  • 1Department of Respiratory and Sleep Disorders Medicine, Western Hospital, Footscray, Victoria, Australia. michael.flynn@wh.org.au

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|January 13, 2012
PubMed
Summary

Post-migration screening for tuberculosis (TB) in immigrants with abnormal chest radiographs identified a high prevalence of TB. This targeted approach effectively detects cases, improving public health outcomes.

Related Experiment Videos

Last Updated: May 25, 2026

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
09:57

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

Area of Science:

  • Public Health
  • Infectious Disease Epidemiology
  • Immigration Health

Background:

  • Immigrants are screened for tuberculosis (TB) post-migration, particularly those with abnormal chest radiographs (CXR).
  • Understanding TB prevalence and incidence in this population is crucial for effective public health strategies.
  • The TB health undertaking (TBU) system in Victoria, Australia, facilitates post-migration screening.

Purpose of the Study:

  • To determine the prevalence of TB at entry, screening yield, and incidence among immigrants undergoing post-migration screening.
  • To assess TB rates in individuals selected for screening due to abnormal CXRs.
  • To compare TB prevalence between on-shore and off-shore TBU applicants.

Main Methods:

  • Utilized a TB screening clinic database linked with the Victorian TB database.
  • Calculated rates of notified TB, including prevalence at entry and incidence.
  • Analyzed data from 1996-2006 for immigrants in Victoria, Australia.

Main Results:

  • Prevalence at entry was 505/100,000, with a screening yield of 420/100,000.
  • Incidence between 6-12 months post-screening was 160/100,000 person-years.
  • On-shore TBU applicants had a seven-fold higher prevalence (1876/100,000) than off-shore applicants (254/100,000).
  • Abnormal CXR combined with a tuberculin skin test ≥ 15 mm showed a TB prevalence of 2907/100,000.

Conclusions:

  • Selective post-migration screening for TB is effective in identifying a significant number of cases.
  • Targeted screening based on risk factors like abnormal CXR and positive tuberculin skin tests enhances detection rates.
  • The findings support the continued use and refinement of post-migration screening programs for TB control.