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Updated: May 25, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Benchmarking: applications to transfusion medicine.

Torunn Oveland Apelseth¹, Laura Molnar, Emmy Arnold

¹Department of Immunology and Transfusion Medicine, Haukeland University Hospital, Bergen, Norway. torunn.oveland.apelseth@helse-bergen.no

Transfusion Medicine Reviews

|January 13, 2012

Summary

Benchmarking in transfusion medicine requires structured comparisons to improve practices. The sentinel site model offers a sustainable starting point for initiating benchmarking programs.

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Last Updated: May 25, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Area of Science:

Transfusion Medicine
Healthcare Quality Improvement
Health Services Research

Background:

Benchmarking is a structured process for improving practices through comparative analysis.
Its application in transfusion medicine is crucial for enhancing patient care and operational efficiency.

Purpose of the Study:

To identify studies on benchmarking in transfusion medicine.
To summarize existing benchmarking approaches and challenges.
To provide recommendations for advancing benchmarking in the field.

Main Methods:

A systematic review of published literature was conducted.
Studies compared at least two institutions or regions.
Focus areas included blood utilization, safety, operational aspects, and blood donation.

Main Results:

Forty-five studies were included, with a focus on blood utilization (35 studies).
Seven studies were classified as benchmarking, two as trending, and 36 as single-event.
Three benchmarking models were identified: regional, sentinel site, and institutional-initiated.

Conclusions:

Benchmarking approaches are needed in transfusion medicine.
Key challenges include defining best practices and cost-effective data collection.
The sentinel site model is recommended as a starting point, with the regional model as an ideal goal.