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Serum antioxidant vitamin levels in patients with coronary heart disease

Hilal Yıldıran1, Seyit Mehmet Mercanlıgil, Halit Tanju Besler

  • 1Gazi University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Besevler, Ankara, Turkey. ciftcihilal@hotmail.com

International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition
|January 13, 2012
PubMed

Insights

Men with coronary heart disease (CHD) exhibit higher fat mass and lower serum antioxidant vitamin levels. These factors, along with lower high-density lipoprotein cholesterol (HDL-C), may indicate increased CHD risk.

Area of Science:

  • Cardiology
  • Nutritional Science
  • Human Physiology

Background:

  • Coronary heart disease (CHD) is a leading cause of mortality.
  • Understanding risk factors beyond traditional markers is crucial for prevention and management.

Purpose of the Study:

  • To investigate anthropometric measurements, body composition, and serum antioxidant vitamin levels in men with CHD.
  • To compare these parameters between men with and without CHD.

Main Methods:

  • Cross-sectional study comparing 35 men with CHD and 31 men without CHD (aged 40-65).
  • Data collection included dietary records, anthropometric measurements, and analysis of serum antioxidant vitamins and lipid profiles.

Main Results:

  • Men with CHD had significantly higher fat mass (FM) and fat mass percentage (FM%).
  • Lower high-density lipoprotein cholesterol (HDL-C) levels were observed in men with CHD.
  • Serum levels of vitamins A, E, and C were significantly lower in men with CHD compared to controls.

Conclusions:

  • Elevated fat mass, reduced HDL-C, and lower serum antioxidant vitamin levels are potential risk factors for coronary heart disease.
  • These findings suggest a role for body composition and micronutrient status in CHD pathogenesis.

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