[Pulmonary aspergillosis complicating atypical mycobacterial infection in two patients suffering from chronic

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E Montaigne1, F X Petit, A L Gourdier

  • 1Lunam université, 49933 Angers, France.

Revue Des Maladies Respiratoires
|January 14, 2012
PubMed
Abstract

Insights

Opportunistic Aspergillus pulmonary disease can complicate atypical mycobacterial infections in patients with chronic obstructive pulmonary disease (COPD). A systematic search for pulmonary aspergillosis is recommended during follow-up of these patients.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Mycology

Background:

  • Atypical mycobacteria and Aspergillus are opportunistic pathogens causing severe lung disease.
  • Chronic obstructive pulmonary disease (COPD) and immunosuppression increase susceptibility.
  • These infections pose diagnostic and therapeutic challenges.

Observation:

  • Two cases of alcoholic patients with emphysematous COPD are presented.
  • Patient 1 developed chronic necrotizing aspergillosis after Mycobacterium avium infection.
  • Patient 2 developed an aspergilloma after Mycobacterium xenopi infection.

Findings:

  • Pulmonary aspergillosis can complicate atypical mycobacterial infections.
  • This co-infection may lead to poor treatment response.
  • The association presents significant diagnostic and therapeutic hurdles.

Implications:

  • A systematic screening for pulmonary aspergillosis is crucial in patients with atypical mycobacterial infections.
  • Early detection and management can improve patient outcomes.
  • Understanding this co-infection is vital for effective patient care.

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