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Protein carbonyl groups in trained subjects
R Lo Presti1, B Canino, M Montana
1Dipartimento di Medicina Interna e Specialistica, Università di Palermo, Palermo, Italy.
Regular physical activity, particularly endurance and mixed sports, reduces plasma protein carbonyls (PC), indicating enhanced protection against oxidative stress. Power sports did not show this effect.
Area of Science:
- Exercise Physiology
- Biochemistry
- Oxidative Stress Research
Background:
- Oxidative stress is implicated in various physiological and pathological processes.
- Physical activity is known to influence oxidative stress markers.
- Plasma protein carbonyls (PC) are a marker of protein oxidation.
Purpose of the Study:
- To evaluate plasma protein carbonyl groups (PC) in trained subjects (TS) practicing different types of sports.
- To compare PC levels in TS with sedentary controls (SC).
- To investigate potential differences in PC levels based on sport type (endurance, mixed, power) and sex.
Main Methods:
- Enzyme-linked immunosorbent assay (ELISA) was used to measure PC levels in fasting venous blood.
- Subjects were categorized into endurance, mixed, or power sports groups.
- Trained subjects (n=81) were compared to sedentary controls.
Main Results:
- A significant decrease in PC was observed in the overall group of TS compared to SC.
- TS practicing endurance and mixed sports showed decreased PC concentrations.
- No significant decrease in PC was found in subjects practicing power sports; no sex differences were observed.
Conclusions:
- Endurance and mixed sports training enhance the protection of body proteins against oxidative stress.
- Regular physical activity, especially aerobic exercise, is beneficial for mitigating oxidative damage.
- These findings support the promotion of regular physical activity for health benefits.
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