Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Network study of integrated biochemical switching system. I: Connection of basic elements.

M Okamoto1, K Hayashi

  • 1Department of Biochemical Engineering and Science, Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka, Japan.

Bio Systems
|January 1, 1990
PubMed
Summary

This study simulates artificial neuronic devices, revealing how excitatory stimuli affect switching properties. Key findings include stimulus-dependent excitation and the observation of long-term potentiation with varied stimuli.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Purification and amino-acid sequence of a nerve growth factor from the venom of Vipera russelli russelli.

Biochimica et biophysica acta·1992
Same author

Genomic structure of the human caldesmon gene.

Proceedings of the National Academy of Sciences of the United States of America·1992
Same author

Crosslinking of proteins in acetylcholine receptor-rich membranes from Torpedo californica: relation of 43-kD protein and Torpedo dystrophin to acetylcholine receptor.

Biochemistry international·1992
Same author

[The first cholera case diagnosed early in the clinical laboratory by DNA probe method].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases·1992
Same author

Transesophageal echocardiographic diagnosis of coronary sinus type atrial septal defect.

American heart journal·1992
Same author

[Phase I study of NK 622 (toremifene citrate)].

Gan to kagaku ryoho. Cancer & chemotherapy·1992

Area of Science:

  • Computational Neuroscience
  • Biochemical Systems Engineering

Background:

  • Building upon Rosen's work and prior research, this study initiates network investigations.
  • Focuses on integrated biochemical switching systems as precursors to artificial neuronic devices.

Purpose of the Study:

  • To examine the impact of excitatory stimuli on the switching characteristics of a proposed artificial neuronic system.
  • To understand signal transmission, amplification, and potentiation within these biochemical systems.

Main Methods:

  • Computer simulations were employed to model and analyze the behavior of the biochemical switching systems.
  • Investigated the effects of single and multiple excitatory stimuli with varying parameters.

Main Results:

Related Experiment Videos

  • The number of excited elements correlated directly with the excitatory stimulus's intensity.
  • Delayed stimuli failed to transmit, while signals showed amplification followed by attenuation.
  • Long-term potentiation was observed by manipulating multiple stimuli frequencies.
  • Reversible interactions between elements led to continuous output switching.

    • Conclusions:

    • The simulated artificial neuronic devices exhibit stimulus-dependent switching behaviors.
    • Demonstrated signal amplification, attenuation, and the potential for long-term potentiation.
    • Suggests the viability of these systems for modeling neural network dynamics.