Related Experiment Video
Updated: May 25, 2026
08:31
Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
[Acute myeloid leukemia with t(16;21)(q24;q22) in a child]
Yoriko Noguchi1, Yuji Nakamachi, Chinami Oyabu
1Department of Clinical Laboratory, Kobe University Hospital.
[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|January 14, 2012
Abstract:
The t(16;21)(q24;q22), a rare chromosomal translocation observed mostly in therapy-related acute myelogenous leukemia (AML), produces a RUNX1-CBFA2T3 fusion gene. Here we report a de novo AML case of 1-year-old girl with t(16;21)(q24;q22). In this case, we demonstrated the RUNX1-CBFA2T3 fusion gene and established quantitative RT-PCR for detecting minimal residual disease.
