Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

HLA 1990.

W R Mayr1

  • 1Institute for Transfusion Medicine, Rheinisch-Westfälische Technische Hochschule, Aachen, Federal Republic of Germany.

Blut
|October 1, 1990
PubMed
Summary
This summary is machine-generated.

The Human Leukocyte Antigen (HLA) system, crucial for T lymphocyte antigen recognition, comprises numerous genetic polymorphisms. Future research will focus on understanding these complex HLA polymorphisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

West Nile virus lineage 2 infection in a blood donor from Vienna, Austria, August 2014.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2015
Same author

Detection of granulocyte-reactive antibodies: a comparison of different methods.

Vox sanguinis·2015
Same author

DNA Commission of the International Society for Forensic Genetics: revised and extended guidelines for mitochondrial DNA typing.

Forensic science international. Genetics·2014
Same author

Granulocyte-reactive antibodies are associated with red blood cell alloimmunization.

Vox sanguinis·2014
Same author

The use of the electronic (computer) cross-match.

Vox sanguinis·2013
Same author

DNA commission of the International Society of Forensic Genetics: Recommendations on the evaluation of STR typing results that may include drop-out and/or drop-in using probabilistic methods.

Forensic science international. Genetics·2012
Same journal

Clostridial septicaemia with intense hemolysis complicating septic abortion.

Blut·1990
Same journal

Improvement of pneumonia and arthritis in Felty's syndrome by treatment with granulocyte-macrophage colony-stimulating factor (GM-CSF).

Blut·1990
Same journal

Flow cytometric analysis of tissue factor (TF) expression on stimulated monocytes--comparison to procoagulant activity of mononuclear blood cells.

Blut·1990
Same journal

Coagulopathy after snake bite by Bothrops neuwiedi: case report and results of in vitro experiments.

Blut·1990
Same journal

Septicemia due to Streptococcus mitis in neutropenic patients with acute leukemia.

Blut·1990
Same journal

Variations in erythropoiesis throughout a lifetime. Studies in a high-leukaemic mouse strain, the AKR/O strain, and a non-leukaemic strain, the WLO strain.

Blut·1990
See all related articles

Area of Science:

  • Immunogenetics
  • Human Genomics
  • Molecular Biology

Background:

  • The Human Leukocyte Antigen (HLA) system constitutes a significant portion of the human genome.
  • HLA molecules are essential for T lymphocyte-mediated antigen recognition.
  • The HLA system is characterized by extensive genetic and phenotypic polymorphisms.

Purpose of the Study:

  • To describe the phenotypically expressed and genomic polymorphisms within the HLA system.
  • To discuss the primary objectives for future research concerning HLA polymorphisms.

Main Methods:

  • Genomic analysis of the HLA system.
  • Phenotypic characterization of HLA expression.
  • Literature review and synthesis of current research.

Related Experiment Videos

Main Results:

  • Detailed description of various polymorphisms within the HLA system.
  • Identification of key areas for future investigation in HLA research.

Conclusions:

  • The HLA system's polymorphisms are critical for immune responses.
  • Further research is needed to fully elucidate the functional implications of HLA diversity.