Septic thrombosis of the cavernous sinus secondary to a Streptococcus milleri oral infection

B Imholz1, M Becker, T Lombardi

  • 1Service of Oral and Maxillofacial Surgery, Department of Surgery, Hôpitaux Universitaire de Genève, Faculty of Medicine, Switzerland.

Insights

Septic thrombosis of the cavernous sinus (STCS) is a rare but serious condition. This case highlights oral infections as an unusual cause of STCS, emphasizing the need for oral cavity examination in intracranial infections.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Otolaryngology

Background:

  • Septic thrombosis of the cavernous sinus (STCS) is a rare, potentially lethal condition.
  • Common causes include sphenoid/ethmoid sinusitis and facial infections, often due to Staphylococcus aureus or Streptococcus pneumoniae.
  • Oral infections are an exceptionally rare etiology for STCS.

Observation:

  • A case of acute STCS secondary to generalized Streptococcus milleri periodontitis is presented.
  • This highlights an unusual pathway for intracranial infection.
  • Streptococcus milleri group represents an uncommon pathogen in this context.

Findings:

  • The study identifies oral infections, specifically Streptococcus milleri periodontitis, as a rare but possible cause of septic thrombosis of the cavernous sinus.
  • This underscores the potential for pathogens from the oral cavity to spread to intracranial structures.

Implications:

  • Clinicians should consider a thorough oral cavity examination in patients with intracranial infections, particularly those involving uncommon pathogens.
  • Early identification of oral foci can lead to timely intervention and improved patient outcomes in STCS.
  • This case expands the known spectrum of infectious etiologies for STCS.

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