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Updated: May 25, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
[Superior vena cava thrombosis in a case with low serum factor XII]
Yasumasa Shundo1, Tsuyoshi Takahashi, Toru Itaya
1Department of Thoracic Surgery, Fujieda Municipal General Hospital, Fujieda, Japan.
Abstract:
The present case is 74 years old man who was hospitalized to treat lung tumor suspected of malignancy. Because the superior vena cava thrombus was also revealed by radiological examination, he was performed lobectomy and thrombectomy at the same time. He has past history of intravenous hyperalimentation for 15 days, and we supposed the event to be the cause of the thrombus. Venous thrombus has developed again in the left subclavian vein in spite of the anticoagulant therapy at the early postoperative period. The level of serum factor XII turned out to be low by the precise examination, of which possible contribution to thrombus formation was suspected.
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