[Development of antibacterial plastic biliary stent coated with nano-silver]

The common complications of the endoprosthesis are occlusion of the stents, and cholangitis. There are many bacterial colonies in the blocked stents. Some studies have proved that the silver in a low concentration has the antimicrobial efficacy .The plastic biliary stents coated with nano-silver were prepared by the chemical redox process with plastic stents as carriers and silver nitrate as material. Then the friction coefficient and elastic modulus of the stents were detected by use of scanning electron microscope (SEM), transmission electron microscopy (TEM) and Energy Dispersive X-ray analysis (EDXA), scanning tunneling microscope (STM). The result shows that the nano-sliver coating is high purity and the nanoparticle is well-distributed, range of size is 5-80 nm. Antibacterial plastic biliary stents coated with nano-sliver that its surface is smooth and elasticity is not obvious change.