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Published on: October 29, 2014
Adult intussusception: presentation, management, and outcomes of 148 patients
Rachel A Lindor1, M Fernanda Bellolio, Annie T Sadosty
1Mayo Medical School, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Insights
Adult intussusception, though rare, often presents with abdominal pain, nausea, and vomiting. Early recognition is crucial as some cases are asymptomatic and may require surgical intervention.
Area of Science:
- Gastroenterology
- Abdominal Surgery
Background:
- Intussusception is primarily a pediatric condition, with limited characterization in adults.
- Undiagnosed adult intussusception can lead to significant morbidity, emphasizing the need for early clinical recognition.
Purpose of the Study:
- To describe the clinical presentation, management, disposition, and outcomes of adult intussusception over a 13-year period.
- To enhance understanding of adult intussusception for improved diagnosis and treatment.
Main Methods:
- Retrospective study of adult intussusception cases at a tertiary academic center (1996-2008).
- Case identification via International Classification of Diseases, 9th Revision codes and document search.
- Duplicate data abstraction by two independent authors for accuracy.
Main Results:
- 148 adult patients were analyzed; common symptoms included abdominal pain (72%), nausea (49%), and vomiting (36%).
- 20% of cases were asymptomatic, often diagnosed incidentally.
- Patients presenting to the emergency department (ED) had higher rates of symptoms and surgical intervention.
Conclusions:
- Adult intussusception frequently manifests with abdominal pain, nausea, and vomiting, but asymptomatic presentations occur.
- Identifying a lead point or ileocolonic location increases the likelihood of surgical intervention for adult intussusception.
Background:
Intussusception is a predominantly pediatric diagnosis that is not well characterized among adults. Undiagnosed cases can result in significant morbidity, making early recognition important for clinicians.
Study Objectives:
We describe the presentation, clinical management, disposition, and outcome of adult patients diagnosed with intussusception during a 13-year period.
Methods:
A retrospective study of consecutive adult patients diagnosed with intussusception at a tertiary academic center was carried out from 1996 to 2008. Cases were identified using International Classification of Diseases, 9(th) Revision codes and a document search engine. Data were abstracted in duplicate by two independent authors.
Results:
Among 148 patients included in the study, the most common symptoms at presentation were abdominal pain (72%), nausea (49%), and vomiting (36%). Twenty percent were asymptomatic. Sixty percent of cases had an identifiable lead point. Patients presenting to the emergency department (ED) (31%) had higher rates of abdominal pain (relative risk [RR] 5.7) and vomiting (RR 3.4), and were more likely to undergo surgical intervention (RR 1.8) than patients diagnosed elsewhere. There were 77 patients who underwent surgery within 1 month; patients presenting with abdominal pain (RR 2.2), nausea (RR 1.7), vomiting (RR 1.4), and bloody stool (RR 1.9) were more likely to undergo surgery.
Conclusions:
Adult intussusception commonly presents with abdominal pain, nausea, and vomiting; however, approximately 20% of cases are asymptomatic and seem to be diagnosed by incidental radiologic findings. Patients presenting to an ED with intussusception due to a mass as a lead point or in an ileocolonic location are likely to undergo surgical intervention.
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